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Advances in Type 2 Inflammatory Disease

Understand the key pathways involved in Type 2 inflammation in asthma.

Critical Roles for Type 2 Cytokines in the Pathobiology of Asthma

Michael S. Blaiss, MD, FACAAI

10m 15s

Airway Remodelling in Asthma: Key Roles for Type 2 Inflammation

Reynold A. Panettieri, Jr. MD

12m 54s

1. Introduction

2. Learning Objectives

3. Overview of Type 2 Inflammation in Asthma

4. Important Cells and Cyrokines Involved in Type 2 Inflammation and Asthma

5. Diverse Manifestation of Type 2 Inflammation in Asthma

6. How IL-5 Contributes to Type 2 Inflammation

7. IL-4 and IL-13 Contributions To Type 2 Inflammation

8. IL-4Rα Involvement in IL-4 and IL-13 Signalling

1. Introduction

2. Learning Objectives

3. Potential Consequences of Airway Remodelling in Asthma - Part 1

4. Potential Consequences of Airway Remodelling in Asthma - Part 2

5. Correlating The Airway Epithelial Remodelling Effect With Disease Severity

6. Type 2 Inflammation Contribution to Airway Remodelling and Pathogenesis

7. Evidence that Increased Remodelling Correlates with High Levels of Type 2 Inflammation

8. Consequences of Asthma Compared to Increased Levels of Mucus Plugging

9. Type 2 Inflammation and Airway Obstruction Correlates with Mucus Plugging

10. Correlation Between Increased MU5AC Gene Expression and Mucus Plugging

11. Examining How IL-13 is Activating Cells

12. Allergens, Viruses and Microbes Activate Airway Smooth Muscle Cells to Activate IL-4 and IL-13

13. Overview of Aspects Covered

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Critical Roles for Type 2 Cytokines in the Pathobiology of Asthma

Michael S. Blaiss, MD, FACAAI

10m 15s
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Airway Remodelling in Asthma: Key Roles for Type 2 Inflammation

Reynold A. Panettieri, Jr. MD

12m 54s